Know Cancer

forgot password

Exercise Intervention in Breast Cancer Patients With Treatment-Induced Arthralgia

18 Years
Not Enrolling
Breast Cancer, Arthralgia

Thank you

Trial Information

Exercise Intervention in Breast Cancer Patients With Treatment-Induced Arthralgia

Inclusion Criteria:

- Post menopausal women with a history of estrogen positive breast cancer who are
receiving aromatase inhibitors for at least one month.

- Patients must complain of mild to moderate arthralgia.

- Ability to understand and sign informed consent.

- Patients meet criteria for low to moderate risk for moderate exercise based oon the
ACSM guidelines.

Exclusion Criteria:

- Inability to comply with study requirements.

- Metastatic breast cancer.

- Patients with orthopedic or neuromuscular disorders that preclude participation in

- Rheumatoid arthritis.

- History of MI, angina or congestive heart failure.

- Pregnant or lactating females.

- Patients that are high risk for moderate exercise based on ACSM risk classification.

- Patients who exceed minimal physical activity recommendations from the US Surgeon
General's Report: Accumulation of 30 minutes or more of moderate physical activity on
most days of the week.

- Morbidly obese with BMI ≥ 40

Type of Study:


Study Design:

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention

Outcome Measure:

Effects of exercise

Outcome Description:

To assess the effect of an exercise intervention in breast cancer patients with arthralgia secondary to adjuvant treatment with aromatase inhibitors.

Outcome Time Frame:

Length of study

Safety Issue:


Principal Investigator

Tracy O'Connor, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Roswell Park Cancer Institute


United States: Institutional Review Board

Study ID:

I 169310



Start Date:

March 2010

Completion Date:

Related Keywords:

  • Breast Cancer
  • Arthralgia
  • Arthralgia
  • Breast Neoplasms



Roswell Park Cancer InstituteBuffalo, New York  14263