Prevention of Post-Mastectomy Breast Pain Using Ambulatory Continuous Paravertebral Blocks
Specific Aim 1: To determine if, compared with current and customary analgesia, the
addition of a multiple-day ambulatory continuous paravertebral block decreases the incidence
and severity of post-mastectomy pain.
Hypothesis 1: Following mastectomy, the incidence and severity of breast pain will be
significantly decreased in the week following surgery with a multiple-day ambulatory
continuous paravertebral block as compared with patients receiving standard-of-care
treatment (as measured on the 11-point numeric rating scale).
Hypothesis 2: Following mastectomy, the incidence and severity of chronic pain will be
significantly decreased three months following multiple-day ambulatory continuous
paravertebral blocks as compared with patients receiving standard-of-care treatment (as
measured on the 11-point numeric rating scale).
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Pain Scores (NRS)
Pain score on the 0-10 Numeric Rating Scale given as part of the Brief Pain Inventory
Day following Surgery
Brian M Ilfeld, M.D., M.S.
University of California, San Diego, Department of Anesthesia
United States: Institutional Review Board
PVB Catheter Study
|UCSD Thornton Hospital||La Jolla, California 92037|