Study the Role of Stem Cell in Curing Drug Induced Liver Injury in Metastatic Breast Cancer
1. The researcher investigate the incidence and the cause of Drug Induced Liver Injury in
2. Patients having a complete clinical history and physical examination, receive routine
3. Venous blood Sample(4 ml)is collected before and after each cycle according to the
4. Genomic DNA,RNA and upper serum is isolated. ELISA、rt-PCR or PCR-direct sequencing is
used to detect the protein or gene expression associated with liver function.
Observational Model: Cohort, Time Perspective: Cross-Sectional
Protective effection of peripheral hematopoietic stem cell infusion for DILI
Patients receiving PHSC infusion after chemotherapy will have lower incidence of DILI. PHSC infusion may improve the liver function.
XU LIANG, MD and PhD
Beijing Cancer Hospital
China: Ministry of Health