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Distribution of Regional Lung Function, as Determined by the Vibration Response Image Generated by the VRI-2000 System as Compared With Standard Radio-nuclear Method


N/A
18 Years
85 Years
Not Enrolling
Both
Emphysema, COPD

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Trial Information

Distribution of Regional Lung Function, as Determined by the Vibration Response Image Generated by the VRI-2000 System as Compared With Standard Radio-nuclear Method


Patients diagnosed with moderate-to-severe COPD by lung function studies and clinical
evaluation presented in stable clinical condition and were evaluated by lung sound
recordings and quantitative V/Q lung scintigraphy. Regional signals (percentage of lung
sounds) for left and right lungs were compared with the corresponding regional count
percentages of each radionuclide scan, by V/Q scan regions of interest.


Inclusion Criteria:



- Patient is able to read and understand the Informed Consent Form and he/she will
provide written Informed Consent.

- Male or female in the age range of 18-85 years.

- The patient will undergo V/Q scan (up to ONE WEEK from the VRI recording)

- The patient presented for evaluation of COPD.

- Body Mass Index >21.

Exclusion Criteria:

- Unstable clinical status such as fever, acute shortness of breath, cough, hemoptysis,
cheat pain, or acute chest illness.

- Chest wall deformation;

- Spine deformation (including severe scoliosis);

- Hirsutism;

- Potentially contagious skin lesion on the back;

- Skin lesion that would interfere with sensor placement;

- Any additional chronic lung disease of any findings such as past tuberculosis,
visualized on CXR.

8. Previous resection lung surgery and history of lung tumor; 9. Cardiac pacemaker or
implantable defibrillator

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

Comparison of regional lung vibration energy with regional lung function

Outcome Description:

To map regional lung vibration energy in patients with emphysema by using the lung image generated by the VRI system and compare findings to distibution of perfusion and ventilation in standard V/Q scans

Safety Issue:

No

Principal Investigator

Issahar Ben-Dov, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Chaim Sheba Medical Center

Authority:

Israel: Ministry of Health

Study ID:

DB010

NCT ID:

NCT01229020

Start Date:

February 2004

Completion Date:

January 2006

Related Keywords:

  • Emphysema
  • COPD
  • Emphysema
  • COPD
  • lung sounds
  • vibration response imaging
  • Emphysema
  • Pulmonary Emphysema
  • Pulmonary Disease, Chronic Obstructive

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