Inclusion Criteria:

- Curative surgery for carcinoma performed at least three months prior to treatment
start

- Age ≥18 years

- ECOG Performance status (PS): 0

- Life expectancy: at least 3 months

- Laboratory requirements:

- White Blood Count (WBC) ≥ 3 x 109/L

- Absolute neutrophil count (ANC) ≥ 1.5 x 109/L

- Platelet count ≥ 100 x 109/L

- Haemoglobin ≥ 10.0 g/dL

- Total bilirubin level ≤ 1.5 ULN

- AST and ALT ≤ 2.5 x ULN

- Creatinine ≥ 1.5 ULN

- Albumin > 30 g/L

- No expectation of anti-cancer therapy or immunotherapy during the trial period,
hormone therapy given as adjunctive or contraceptive therapy is permitted

- Must be willing to practice acceptable barrier methods of birth control to prevent
pregnancy

- The patient is willing and able to comply with the protocol and agrees to return to
the hospital for follow-up visits and examination

- The patient has been fully informed about the study and has signed the informed
consent form

Exclusion Criteria:

- Has received an investigational drug within 4 weeks prior to study drug
administration, or is scheduled to receive one during the treatment or the
post-treatment period

- Has received immunotherapy or been vaccinated within 12 weeks prior to study drug
administration or has not recovered from adverse events due to such agents

- Has received external radiotherapy or cytotoxic chemotherapy within the last 4 weeks
prior to study drug administration, or has not recovered from adverse events (< Grade
1) due to agents administered more than 4 weeks earlier

- Has received imiquimod within 12 weeks prior to study drug administration or has not
recovered from associated adverse events

- Is currently on any agent with a known effect on the immune system

- Has any other serious illness or medical condition such as but not limited to:

- Any uncontrolled infection or infection requiring antibiotics

- Uncontrolled cardiac failure Classification III or IV (New York Heart
Association)

- Uncontrolled systemic and gastro-intestinal inflammatory conditions

- Bone marrow dysplasia

- History of auto-immune disease

- History of adverse reaction to vaccines

- Known history of positive tests for HIV/AIDS, hepatitis B or C

- Is pregnant or breastfeeding