The Impact of Adnexal Involvement of the Severity and Prognosis of Chronic Graft-versus-Host Disease
- At the initial visit, participants will have a complete examination of their skin, hair
and nails. We will also test muscle strength and movement by moving the participant's
arms, legs and neck. Photographs will be taken of the skin, hair and nails of they are
abnormal. Blood tests will be done to check the liver and blood cell count. The
participant and their legal guardian will answer questions about how the participant
feels and about their health.
- Participants will then be scheduled for follow up visits at 3 months, 6 months, and 12
months. At each subsequent visit the following will be done: A complete examination of
the skin, hair and nails; a test of muscle strength; photographs will be repeated;
blood tests to check liver and blood cell counts; and questions about how the
participant feels and about their health.
Observational Model: Case-Only, Time Perspective: Prospective
To determine if adnexal involvement predicts worse severity and/or prognosis in chronic GVHD. This will be measured by administration of systemic therapy other than steroids.
Jennifer Huang, MD
Children's Hospital Boston
United States: Institutional Review Board
|Dana-Farber Cancer Institute||Boston, Massachusetts 02115|
|Children's Hospital Boston||Boston, Massachusetts 02115|