Cancer Survival Through Weight Loss and Exercise (CASTLE)
This study will be divided into two phases (Phase I and II) that will differ by the
intensity of motivational intervention. In Phase I, participants will receive 6 months of
intensive weekly group-based or telephone-based motivational, behavior modifying
intervention aimed at improving physical activity levels and dietary habits. Phase II will
be an additional 6 months of monthly individualized motivational intervention in order to
attain and maintain at least 7% body weight loss. All participants will attend an
orientation, 2 run-in sessions, and a baseline assessment prior to the intervention.
Participants will then be assigned to either the group based intervention or telephone
intervention. The first 30 participants will enter into the group-based intervention and the
second 30 will enter into the telephone-based intervention. Follow-up visits will be
completed at the end of Phase I (week 25) and Phase II (week 50). Up to 60 women with a
previous history of breast cancer will participate in this study.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment
To examine the effectiveness of using motivational, behavioral interventions aimed at improving physical activity levels and dietary habits to produce weight loss in women with a history of breast cancer.
Timothy S Church, MD, MPH, PhD
Pennington Biomedica Research Center
United States: Federal Government
|Pennington Biomedical Research Center||Baton Rouge, Louisiana 70808|