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A Study Investigating the Predictive Value of Philadelphia Positive Stem Cell Properties in Newly Diagnosed Patients With Chronic Myeloid in Chronic Phase Receiving Treatment With Imatinib


N/A
18 Years
N/A
Open (Enrolling)
Both
Chronic Myeloid Leukemia

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Trial Information

A Study Investigating the Predictive Value of Philadelphia Positive Stem Cell Properties in Newly Diagnosed Patients With Chronic Myeloid in Chronic Phase Receiving Treatment With Imatinib


Inclusion Criteria:



- Diagnosis of CML in chronic phase.

- ECOG <2.

- Normal organ function and ULN Total bili, AST and ALT.

- Must have the ability to understand and sign a written consent form

Exclusion Criteria:

- Patients may not be receiving any other investigational agents.

- May not have prior treatment with Imatinib, Dasatinib, Nilotinib or other tyrosine
kinase inhibitors.

- Patients must not have uncontrolled intercurrent illness including, but not limited
to, ongoing or active infections, symptomatic congestive heart failure, unstable
angina pectoris, cardiac arrhythmias, or psychiatric illness/social situations that
would limit compliance with study requirements.

- Pregnant or nursing mothers

- Patients must have no prior malignancies except for; adequately treated non-melanoma
skin cancer, cervical carcinoma-in-situ, adequately treated Stage I or II cancer from
which the patient is in complete remission, or any other cancer from which the
patient has been disease free for 5 years

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Principal Investigator

Xiaoyan Jiang

Investigator Role:

Study Director

Investigator Affiliation:

University of British Columbia - Terry Fox Laboratory

Authority:

Canada: Health Canada

Study ID:

H09-03255

NCT ID:

NCT01215487

Start Date:

October 2010

Completion Date:

October 2015

Related Keywords:

  • Chronic Myeloid Leukemia
  • CML Predictive Study
  • Leukemia
  • Leukemia, Myeloid
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive

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