Inclusion Criteria:

- Subject is 50 years old and above

- Subject is asymptomatic and referred for regular recommended screening colonoscopy or
subject is referred due to suspicion of colon cancer, prior to beginning of any
treatment (enriched population)

- Subject signed the informed consent

Exclusion Criteria:

- Subject has been previously diagnosed with any type of cancer

- Subject has been previously diagnosed with a colorectal abnormality such as
colorectal adenoma, hyperplastic polyp or carcinoma

- Blood sample was not collected on the day of colonoscopy and prior to colonoscopy

- Subject has first degree family history of colorectal cancer

- Subject has active infection or inflammation as determined clinically at screening

- Subject is currently taking medications related to the previous exclusion criteria

- Subject has participated in, or is participating in, any investigational drug or
device study within 30 days prior the date of colonoscopy and any additional study
required test

- Pregnant or lactating woman