Clomiphene Citrate Co-treatment With Low Dose HP Urinary FSH vs. HP Urinary FSH Step-up Protocol for Clomiphene-citrate Resistant PCOS Anovulatory Infertility: Randomized Controlled Trial
To test whether CC co- treatment with chronic low dose HP uFSH vs chronic low dose HP uFSH
in CC resistant PCOS will yield better results in terms of ,ovulation rate, lower follicle
number,lower HP uFSH dose ,better outcome in terms of pregnancy rates, better
cost-effectiveness ratio, lower multiple pregnancy rates,lower cycle cancellation.
Interventional
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
ovulation rate
IF CC Co-treatment with low dose step-up HP urinary(u)FSH results in similar or higher ovulation rate compared with step-up low dose HP uFSH
6 months
No
Mohamad E Ghanem, MD
Study Chair
Mansoura Integrated Fertility Center
Egypt:Ministry of health
MansouraIFC1
NCT01212263
January 2010
September 2012
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