Effects of Metformin on the Ovarian Response to Gonadotropins for in Vitro Fertilization Treatment in Patients With Polycystic Ovary Syndrome and Predictors of Poor Ovarian Response
35 Years
45 Years
Female
Infertility, PCOS, Prognosis for Poor Response
Trial Information
Effects of Metformin on the Ovarian Response to Gonadotropins for in Vitro Fertilization Treatment in Patients With Polycystic Ovary Syndrome and Predictors of Poor Ovarian Response
Primary infertile patients with PCOS older than 35 years and/or with a basal
follicle-stimulating hormone (FSH) level higher than 10 IU/L who were scheduled for IVF
cycles were enrolled in the study protocol.
Inclusion Criteria:
- PCOS
- Prognosis for poor response
- Infertility
Exclusion Criteria:
- Male factor infertility
- Tubal infertility
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Outcome Measure:
Rate of cancellation due to low ovarian response
Outcome Description:
Number of cancelled cycles/total cycles
Outcome Time Frame:
one month
Safety Issue:
No
Principal Investigator
Fulvio Zullo, MD
Investigator Role:
Study Chair
Investigator Affiliation:
Department of Obstetrics and Gynecology, University "Magna Graecia" of Catanzaro
Authority:
Italy: The Italian Medicines Agency
Study ID:
02/2010
NCT ID:
NCT01208740
Start Date:
January 2009
Completion Date:
March 2011
Related Keywords:
- Infertility
- PCOS
- Prognosis for Poor Response
- Gonadotropins
- infertility
- IVF
- metformin
- PCOS
- poor prognosis
- poor responder
- Infertility
- Polycystic Ovary Syndrome
Name | Location |
|---|
