The Relationship of Racial Genetic Admixture With Endometrial Cancer Outcomes
- To identify racial categorization as the proportion of genetic background of
African-American or European-American women with endometrioid endometrial cancer (EEC).
- To evaluate the association of racial genetic admixture with clinicopathologic
variables and outcomes.
- To compare the concordance between racial genetic admixture and self-designated race
OUTLINE: This is a multicenter study. Patients are stratified by race (African-American vs
European-American) and disease stage (I vs II vs III vs IV).
DNA from archived frozen normal tissue samples are genotyped for the ancestry informative
markers. Clinicopathological and demographic characteristics associated with each sample are
Proportion of genetic background that is of African-American descent
Rodney P. Rocconi, MD
University of South Alabama Mitchell Cancer Institute