Comparison Study of BioXtra Spray and Mouth Rinse in Patient With Radiation-induced Xerostomia
Xerostomia or dry mouth is an important complication of radiotherapy for head and neck
regions producing serious discomfort for patients with a significant reduction in their
quality of life. Symptomatic treatments for the disease include maintain oral hygiene and
use of artificial saliva substitutes.
Due to limited studies on efficacy compounds BioXtra, present study compared the effects of
spray and mouth rinse BioXtra in symptoms of xerostomia in patients under head and neck
cancer radiotherapy .
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Investigator, Outcomes Assessor), Primary Purpose: Supportive Care
improvement of xerostomia
change of symptoms of xerostomia is measured by Visual Analogue Scale and Dichotomos questionnaire[ Time Frame: baseline compared with measures on day 14
Mahin Bakhshi, DDS/MS
Qazvin University Of Medical Sciences
Iran: Ethics Committee