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Characterization of Rectal Cancer Hypoxia Using pO2 Histography and Immunohistochemistry for Hypoxia-Related Proteins


N/A
18 Years
89 Years
Not Enrolling
Both
Rectal Cancer

Thank you

Trial Information

Characterization of Rectal Cancer Hypoxia Using pO2 Histography and Immunohistochemistry for Hypoxia-Related Proteins


Inclusion Criteria:



- Biopsy proven adenocarcinoma of the rectum. If a biopsy was taken at an outside
hospital, the slides and diagnosis will be reviewed and confirmed by a pathologist at
MSKCC.

- Mid to distal rectal tumors not requiring pre-op radiation or chemotherapy

- Age ≥ 18

- Age < 90

- Karnofsky performance status ≥ 60

- Ability to understand and the willingness to sign a written informed consent
document.

Exclusion Criteria:

- Current pregnancy

- Uncontrolled intercurrent illness that would limit compliance with study
requirements.

Type of Study:

Interventional

Study Design:

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Outcome Measure:

Measure pO2 in rectal cancers

Outcome Description:

Measure pO2 in rectal cancers

Outcome Time Frame:

2 years

Safety Issue:

No

Principal Investigator

José Guillem, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Memorial Sloan-Kettering Cancer Center

Authority:

United States: Institutional Review Board

Study ID:

10-121

NCT ID:

NCT01189877

Start Date:

August 2010

Completion Date:

October 2012

Related Keywords:

  • Rectal Cancer
  • Direct pO2 Measurements
  • 10-121
  • Rectal Neoplasms
  • Anoxia

Name

Location
Memorial Sloan Kettering Cancer Center New York, New York  10021