Inclusion Criteria:

- Age > 18 years old

- Patient with 40 years old and first degree relative affected by colo rectal cancer at
age ≥ 60 ans

- Patient with 40 years old or ten years before the age at affected disease in case or
first deree relative colo rectal cancer before 60 years old.

- Fecal occult blood test positive

- Personal history of adenomatous polyps

- Personnal history of acromegaly

- Patient with social insurance

- Persons already participating in another clinical trial..

- Signature of informed consent

Exclusion Criteria:

- Pregnancy or breast feeding woman

- Déficience mentale du sujet rendant sa participation à l'essai impossible

- Pacemaker or all electronic devices implanted

- Patient with swallowing disorder, or digestive stricture know or suspected by the
investigator

- Previous history of intestinal surgery, radiotherapy or inflammatory bowel disease

- Previous history of polyadenomatous congenital disease, Lynch syndrome

- Intolerance with dompéridon and/or bisacodyl

- Intolerance with oral intake of NaP, polyethylen glycol (PEG) or macrogol

- Colonoscopy contre indication for anesthesiologic reasons