Know Cancer

forgot password

Low-Dose Chest CT for Lung Cancer Screening in Survivors of Hodgkin's Disease

18 Years
Open (Enrolling)
Hodgkin's Lymphoma

Thank you

Trial Information

Low-Dose Chest CT for Lung Cancer Screening in Survivors of Hodgkin's Disease

Inclusion Criteria:

1. 5 years or longer from initial Hodgkin's disease diagnosis

2. Current age 18 or older

3. Received mediastinal irradiation and/or alkylating-agent based chemotherapy

4. Smoking history of 10-pack years or more, or current smoker

Exclusion Criteria:

1. Patients with a history of lung cancer

2. Patients currently receiving treatment for another cancer diagnosis (patients with
another cancer, but currently disease-free and not receiving treatment are eligible)

3. Patients with known diagnosis of any metastatic cancer

4. Pregnant women. Female patients must: be at least one year post-menopausal, have had
a hysterectomy, or have a serum pregnancy test to confirm that they are not pregnant.
These measures must be taken in order to avoid doing a CT scan of a pregnant woman.

Type of Study:


Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Outcome Measure:

Lung cancer detection rate using chest CT screening in patients at increased risk of lung cancer after Hodgkin's disease therapy.

Outcome Time Frame:

5 years

Safety Issue:


Principal Investigator

David Hodgson, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

University Health Network, Princess Margaret Hospital


Canada: Ethics Review Committee

Study ID:

UHN REB 08-0294-CE



Start Date:

August 2010

Completion Date:

October 2013

Related Keywords:

  • Hodgkin's Lymphoma
  • Hodgkin's Lymphoma
  • Lung Cancer
  • Lung Nodule
  • CT scan
  • Hodgkin Disease
  • Lymphoma