Trial Information

Efficacy of a Combined Program for Early Detection of Breast and Gynecological Cancers in Low Resource Countries

We will study the use of sonographic screening in addition to Clinical Breast Examination in
low resource settings where screening programs are not currently in place and establishing a
population based mammographic screening would be expensive, resource intensive, and
difficult if not impossible to implement. The effectiveness of the screening and diagnostic
methodology used for early detection of breast, cervical, ovarian and endometrial cancers in
low resource settings will be studied. The program would involve screening of asymptomatic
women for Breast and Cervical cancer and diagnostic assessment of symptomatic women for
Ovarian and Endometrial cancer. Women in the age group of 30-59 yrs will be screened once
every three years utilizing the following methods: Breast - clinical breast examination
[CBE] and Sonography, followed by Fine needle aspiration biopsy (FNAB) of screen positive
cases; Cervical - Human Papilloma Virus DNA testing followed by Cryotherapy of screen
positive cases (Single visit, screen and treat approach); Ovarian - Transvaginal sonogram
and clinical evaluation; Endometrial - Transvaginal sonographic assessment of the
endometrial stripe.