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Proteomic Analysis of Human Hepatocellular Carcinoma Associated With Portal Vein Thrombosis


N/A
18 Years
75 Years
Open (Enrolling)
Both
Carcinoma, Hepatocellular

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Trial Information

Proteomic Analysis of Human Hepatocellular Carcinoma Associated With Portal Vein Thrombosis


Inclusion Criteria:



Arm A: Hepatocellular carcinoma with vessel invasion:

- hepatocellular carcionoma, pathologic diagnosed.

- image documented vessel invasion, including portal vein thrombosis

- eligible for surgical intervension.

Arm B: hepatocellular carcinoma without vessel invasion:

- hepatocellular carcinoma, pathologic diagnosed or clinical diagnosed according to
EASL criteria.

- no vessel invasion on image.

Arm C: Healthy hepatitis carrier:

- patients age >18 years old with hepatitis B or C

- normal liver function.

Type of Study:

Interventional

Study Design:

Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science

Outcome Measure:

Recurrence

Outcome Description:

Evidence of clinically definite vascular invasion of hepatocellular carcinoma. Confirmed by operation. Compare the proteomic expression of tumor, non-tumor ans tumor tissue in vascular part.

Outcome Time Frame:

one year

Safety Issue:

No

Authority:

Taiwan: Institutional Review Board

Study ID:

97068

NCT ID:

NCT01177631

Start Date:

February 2009

Completion Date:

January 2010

Related Keywords:

  • Carcinoma, Hepatocellular
  • Carcinoma, hepatocellular
  • Portal vein
  • Proteomics
  • Carcinoma
  • Carcinoma, Hepatocellular

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