Effects of Dexamethasone Tapering Schedules on Functional Capacity and Neurocognition in Patients With Newly Diagnosed Glioblastoma Multiforme
The proposed study is a randomized controlled trial. After obtaining written informed
consent, all participants will be randomized to either an abbreviated (14 days) or
protracted (30 days) course of dexamethasone post-operatively.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Functional Capacity (6-minute walk test)
The exercise test is designed to determine how far you can walk in six minutes. This test will take place at the PRT-BTC at Duke University Medical Center and/or Duke University Medical Center inpatient unit on 4100 or 4300 with appropriate medical supervision.
Katherine B Peters, MD, PhD
Duke University Health System
United States: Institutional Review Board