Weight Loss to Prevent BCRL: A Pilot Study
Breast cancer related lymphedema occurs in 20-30% of survivors. Weight loss could prevent
onset. We seek to do a pilot study to establish feasibility of 1) recruiting survivors at
risk for lymphedema to do a weight loss intervention, 2) achieving 10-15% weight loss over
26 weeks in this population, and 3) attendance at follow-up visits 6 months.
- Breast Cancer Survivors who had 5 or more lymph nodes removed and radiation to lymph
nodes as part of treatment.
- Completed all treatments - no metastatic cancers
- Overweight or obese (BMI greater than or equal to 25 kg/m2)
- Medically and logistically able to participate in a weight loss and exercise program
over 6 months.
- Diagnosed with breast cancer within the past 2 years.
- More than 2 years since breast cancer diagnosis
- Medical status that would preclude safety of participation in a weight loss and
- Metastatic cancer
- Already enrolled in a weight loss program
Type of Study:
Observational Model: Cohort
The primary outcome will be the precent of participants who complete 6 month follow-up appointments.
Outcome Time Frame:
United States: Institutional Review Board
- Breast Cancer
- obese women (BMI greater than or equal to 30), do not already have a diagnosis of lymphedema, who are done
- with surgery, chemotherapy, and radiation therapy, and who were diagnosed with breast cancer within the
- past 2 years will be invited to participate.
- Breast Neoplasms
|Abramson Cancer Center of the University of Pennsylvania
||Philadelphia, Pennsylvania 19104-4283