Inclusion Criteria:
- Primitive liver cancer (hepatocellular carcinoma), proved by histology or diagnostic
according to BCLC criteria
- T1-3 N0 M0
- With only one intra hepatic lesion and dimensions between 1 cm and 6 cm (IRM or
hepatic scanner)
- Stereotaxic radiotherapy treatment approved in multidisciplinary consultation, the
patient being rejected for standard therapeutic
- Age >= 18 ans
- Previous anti tumoral treatment allowed but suspended since at least 15 days before
the inclusion
- OMS =< 2
- Portal thrombosis allowed
- Portal high blood pressure allowed
- No contraindication of fiducials implantation, hemostasis disorders must be treated
before the implantation
- In case of underlying cirrhosis, only the Child-Pugh A is allowed
- Life expectancy >= 12 weeks
- Women must have an active contraception during all the study
- Patient affiliated to health insurance
- Patient must sign the consent
Exclusion Criteria:
- T4
- Cirrhosis Child B and C
- Hepatic lesion < 1 cm or > 6 cm
- 2 hepatic lesions or more
- Recurrent or metastatic disease
- Patient already included in another therapeutic trial with an experimental molecule
- Allergy to gold
- Pregnant women or susceptible to be pregnant or breastfeeding
- Unable for medical follow-up (geographic, social or mental reasons)