Prescriptive Exercise Intervention During Active Treatment for Early Stage Breast Cancer Patients: A Breast Cancer Rehabilitation & Exercise Laboratory
Patients (with stage 0 to stage III breast cancer)receiving chemotherapy, radiation or both
chemotherapy and radiation will be included in the study.Randomization will be stratified by
disease stage at diagnosis, treatment modalities planned, and hormonal status. Each patient
will have a weekly goal of 2000 calories burned and 18 MET-hours of exercise which can be
achieved in 4 to 7 hours of physical activity per week. Resistance training, using weight
machines and aerobic training using treadmills, elliptical trainers and stationary bicycles,
will be utilized in the intervention group. The control group will receive basic information
on physical activity but not be instructed. Any physical activity in this group will be
self-reported. Change in C-reactive protein will be the primary endpoint. Changes in other
laboratory values, DEXA measurements, and quality of life measurements will be secondary
endpoints.
Interventional
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care
Changes in CRP
The primary endpoint for this study change in C-reactive protein.
No
Karen Milligan, MD
Principal Investigator
Nevada Cancer Institute
United States: Institutional Review Board
NVCI 10-09
NCT01157130
July 2010
Name | Location |
---|---|
Nevada Cancer Institute | Las Vegas, Nevada 89135 |