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Autoimmune Diabetes: Disease Markers and Treatment of Latent Autoimmune Diabetes in Adults (LADA)


N/A
30 Years
75 Years
Not Enrolling
Both
Autoimmune Diabetes

Thank you

Trial Information

Autoimmune Diabetes: Disease Markers and Treatment of Latent Autoimmune Diabetes in Adults (LADA)


Research has worked out that b-cells are being destroyed by cytokines released from
inflammatory cells. One hypothesis in that T-reg is a cause of autoimmunity, and that T-reg
concentrations are low in patients with newly diagnosed diabetes type 1.

Blood samples will be taken from 10 patients with newly diagnosed type 1 diabetes, Latent
Autoimmune Diabetes in Adults (LADA) and type 1 diabetes older than 10 years and the same
amount of samples from healthy, age- and sex-matched blood donors. Markers of autoimmune
diabetes will be analyzed.


Inclusion Criteria:



- newly diagnosed diabetes type 1

- LADA

- diabetes type 1 older than 10 years

Exclusion Criteria:

- none

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

T-reg

Outcome Description:

??????

Outcome Time Frame:

?

Safety Issue:

No

Principal Investigator

Valdemar Grill, M.D, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Department of Cancer Research and Molecular Medicine

Authority:

Norway:National Committee for Medical and Health Research Ethics

Study ID:

AUTO

NCT ID:

NCT01148238

Start Date:

August 2012

Completion Date:

December 2012

Related Keywords:

  • Autoimmune Diabetes
  • Autoimmune diabetes
  • LADA
  • T-reg
  • cytokine
  • Diabetes Mellitus
  • Diabetes Mellitus, Type 1

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