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N/A
40 Years
N/A
Not Enrolling
Both
Cancer of the Skin

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Trial Information


Inclusion Criteria:



- patient older than 40th, suffering of a C-SCC

- letter of consent signed by the patient

- to be registered to social security

Exclusion Criteria:

- Pregnant women or breastfeeding.

- Small C-SCC (size < 6mm)

- Allergy to Xylocaine

- All vulnerable (minor, adult guardianship…)

Type of Study:

Interventional

Study Design:

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science

Outcome Measure:

miRNAs

Outcome Description:

We will select the miRNAs differently expressed between biopsies obtained respectively from areas of normal, pretumoral and tumoral areas (candidate miRs = miRs potentially involved in tumor transformation of epidermal keratinocytes). This will be assessed by analyzing in each of the biopsies from each patient, the expression of different miRs that are known to date, using a dedicated microarray, then by checking the data obtained by quantitative PCR.

Outcome Time Frame:

1 year

Safety Issue:

No

Principal Investigator

Thierry Passeron, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

CHU de Nice - Service de Dermatologie - Hôpital de l'Archet - 151 Route de saint-antoine de ginestière 06200 Nice

Authority:

France: Ministry of Health

Study ID:

09-PP-05

NCT ID:

NCT01143311

Start Date:

June 2010

Completion Date:

April 2011

Related Keywords:

  • Cancer of the Skin
  • Skin Neoplasms
  • Carcinoma, Squamous Cell

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