Comparison of Billroth-I and Roux-en-Y Reconstruction After Distal Subtotal Gastrectomy for Gastric Cancer Patients : Prospective Randomized Study
Most common procedure for the resection of gastric cancers located in middle or lower
stomach is distal subtotal gastrectomy. However, the optimal reconstruction procedure after
that has still not to be established. Although B-I reconstruction is most common method due
to the safety and simplicity, the duodenal fluid may reflux into the remnant stomach which
may contribute to the mucosal injury to remnant stomach and esophagus. Roux en Y
reconstruction may reduce the reflux to remnant stomach due to the length of Roux en Y limb,
although it is more complicated procedure.
Therefore, we plan to collect 120 patients to compare the degree of reflux between Roux en Y
and Billroth-I reconstructions after distal subtotal gastrectomy for gastric cancer. In
addition, we compare the surgical outcome and quality of life between two groups.
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment
Reflux of bile content
We estimate the degree of reflux by gastrofiberscopic findings using reflux score suggested by Romaganoli. In addition, histological finding of remnant stomach by endoscopic biopsy is also investigated. Reflux symptom is surveyed by Gastrointestinal Symptom Rating Scale.
6 months after surgery
Sang-Uk Han, M.D., Ph D.
Department of Surgery, Ajou University School of Medicine
South Korea: Korea Food and Drug Administration (KFDA)