Mitochondrial Mutations and AML
- To determine whether clonally expanded somatic mitochondrial DNA mutations are
associated with acute myeloid leukemia.
OUTLINE: Genomic DNA from blood samples obtained at diagnosis, remission, and relapse are
analyzed for mitochondrial DNA mutations via PCR.
Association between clonally expanded somatic mitochondrial DNA mutations and acute myeloid leukemia
Jason H. Bielas, PhD
Fred Hutchinson Cancer Research Center
United States: Federal Government