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Effect of Exercise Training on Angiogenesis and Cachexia in Lung Cancer Patients


N/A
40 Years
75 Years
Open (Enrolling)
Both
Non-Small-Cell Lung Cancer

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Trial Information

Effect of Exercise Training on Angiogenesis and Cachexia in Lung Cancer Patients


Inclusion Criteria:



- Age 40-75 years

- Advanced NSCLC

- Eastern Cooperative Oncology Group performance status of 0 or 1

- Targeted therapy for at least 8 weeks

- Stable condition

Exclusion Criteria:

- Severe metastasis, cardiopulmonary or musculoskeletal conditions may affect
participation in exercise

- Do not understand the verbal or written instructions

Type of Study:

Interventional

Study Design:

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Outcome Measure:

Exercise capacity

Outcome Description:

Maximal oxygen consumption with Vmax229 Vastus lateral muscle oxygenation with NIRS

Outcome Time Frame:

8 weeks after the start of the intervention

Safety Issue:

No

Principal Investigator

Ying-Tai Wu, Ph.D

Investigator Role:

Principal Investigator

Investigator Affiliation:

National Taiwan University Hospital

Authority:

Taiwan: Department of Health

Study ID:

201003064R

NCT ID:

NCT01136083

Start Date:

September 2010

Completion Date:

August 2012

Related Keywords:

  • Non-Small-Cell Lung Cancer
  • Tumor
  • Angiogenesis
  • Exercise training
  • VEGF
  • Myostatin
  • Cachexia
  • Carcinoma, Non-Small-Cell Lung
  • Lung Neoplasms

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