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Investigation on the Pharmacokinetic and -Dynamic of Propofol During Awake Craniotomy


N/A
18 Years
N/A
Not Enrolling
Both
Brain Tumor

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Trial Information

Investigation on the Pharmacokinetic and -Dynamic of Propofol During Awake Craniotomy


Inclusion Criteria:



- patients scheduled for awake craniotomy

Exclusion Criteria:

- pregnancy

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Outcome Measure:

prediction error for propofol plasma concentrations

Outcome Description:

On the day of surgery, plasma samples will be drawn during induction, maintenance and recovery from anesthesia. Subsequently the actually measured propofol plasma concentration will be compared with the predicted propofol plasma concentration (according to Marsh et al. and Schnider et al.), and the prediction error will be calculated.

Outcome Time Frame:

day of surgery (day 1)

Safety Issue:

No

Principal Investigator

Martin Soehle, MD, DESA, D habil

Investigator Role:

Principal Investigator

Investigator Affiliation:

Dept. of Anaesthesiology and Intensive Care Medicine, University of Bonn, Germany

Authority:

Germany: Ethics Commission

Study ID:

AC

NCT ID:

NCT01128465

Start Date:

February 2010

Completion Date:

Related Keywords:

  • Brain Tumor
  • propofol
  • awake craniotomy
  • patients requiring an awake craniotomy for brain tumor/lesion resection
  • Brain Neoplasms

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