Investigation on the Pharmacokinetic and -Dynamic of Propofol During Awake Craniotomy
Observational Model: Case-Only, Time Perspective: Prospective
prediction error for propofol plasma concentrations
On the day of surgery, plasma samples will be drawn during induction, maintenance and recovery from anesthesia. Subsequently the actually measured propofol plasma concentration will be compared with the predicted propofol plasma concentration (according to Marsh et al. and Schnider et al.), and the prediction error will be calculated.
day of surgery (day 1)
Martin Soehle, MD, DESA, D habil
Dept. of Anaesthesiology and Intensive Care Medicine, University of Bonn, Germany
Germany: Ethics Commission