Cancer Survivorship in Lynch Syndrome: Impact on Patients and Families
18 Years
N/A
Both
Colorectal Cancer
Trial Information
Cancer Survivorship in Lynch Syndrome: Impact on Patients and Families
Data will be collected primarily using a mailed self-administered questionnaire. A subset of
the participants who complete the mailed questionnaire will be recontacted and invited to
participate in an in-depth, semi-structured telephone interview.
Qualitative Mailed Questionnaires:
Participants will complete a questionnaire that contains questions about your experiences
living with colorectal cancer. The questionnaire should take 45-60 minutes to complete.
Up to 200 colorectal cancer survivors and up to 200 close relatives of colorectal cancer
survivors will take part in this portion of the study.
Telephone Interviews:
In the phone interview, you will be asked some questions about your experiences living with
colorectal cancer. The phone interview should take 30-45 minutes to complete.
Up to 30 colorectal cancer survivors and up to 30 close relatives of colorectal cancer
survivors will take part in this portion of the study.
Inclusion Criteria:
1. Colorectal cancer (CRC) patients with Lynch-syndrome related CRC: Diagnosis of CRC
from 6 months to 5 years prior to enrolling in the study
2. Colorectal cancer (CRC) patients with sporadic CRC: Diagnosis of CRC from 6 months to
5 years prior to enrolling in the study
3. All First-degree relatives (FDRs): Siblings or adult children of recruited CRC
patients
4. All Participants: 18 years of age or older
5. All Participants: Able to read and speak English
6. All Participants: Able to be contacted by mail.
Exclusion Criteria:
1. CRC patients with sporadic CRC: Personal or family history of Lynch syndrome,
familial adenomatous polyposis, inflammatory bowel disease or those who have a FDR
with CRC
2. FDR's: Personal history of cancer
Type of Study:
Observational
Study Design:
Observational Model: Case-Only, Time Perspective: Prospective
Outcome Measure:
Compare Predictors of Health-Related Quality of Life (QOL) among Colorectal Cancer (CRC) Survivors who have Lynch Syndrome (LS) with patients who have Sporadic CRC
Outcome Time Frame:
1 Year
Safety Issue:
No
Principal Investigator
Susan Peterson, PHD, MPH
Investigator Role:
Study Chair
Investigator Affiliation:
UT MD Anderson Cancer Center
Authority:
United States: Institutional Review Board
Study ID:
2010-0160
NCT ID:
NCT01126840
Start Date:
December 2010
Completion Date:
Related Keywords:
- Colorectal Cancer
- Lynch Syndrome
- Families
- Quality of life
- QOL
- First-degree relatives
- Questionnaire
- Interview
- Colorectal Neoplasms
- Colorectal Neoplasms, Hereditary Nonpolyposis
Name | Location |
|---|---|
| UT MD Anderson Cancer Center | Houston, Texas 77030 |
