Inclusion Criteria:

- Chinese women

- Age between 20 and 40 years.

- Confirmed diagnosis of PCOS according to the Rotterdam 2003 criteria (2 out of
3):

1. Oligo- or anovulation

2. Clinical and/or biochemical signs of hyperandrogenism

3. Polycystic ovaries and exclusion of other etiologies (congenital adrenal
hyperplasia, androgen-secreting tumors, Cushing's syndrome)

- At least one patent tube and normal uterine cavity shown by hysterosalpingogram,
HyCoSi or diagnostic laparoscopy within three years.

- Sperm concentration 20×106/mL and progressive motility (grades a and b) ≥50%.

Exclusion Criteria:

- Use of hormonal drugs or other medications including Chinese herbal prescriptions in
the past 3 months.

- Patients with known sever organ dysfunction or mental illness.

- Pregnancy, post-abortion or postpartum within the past 6 weeks.

- Breastfeeding within the last 6 months.

- Not willing to give written consent to the study.