Trial Information
Longitudinal Investigation of Hippocampal Function and Morphology in ALL Patients Treated With Chemotherapy: A Monocentric, Interdisciplinary Pilot Study
Inclusion Criteria:
- Initial diagnosis of acute lymphatic leukaemia (ALL)
- Treatment within the German Multicenter Adult ALL (GMALL 2003) therapy study
- Age 18 to 40 years
- Eligibility for performing study procedure
- Informed consent
Exclusion Criteria:
- Neuropsychiatric disorders
- Present contraindication for MRI investigation (e.g. pacemaker)
Type of Study:
Observational
Study Design:
Observational Model: Case-Only, Time Perspective: Prospective
Outcome Measure:
Hippocampal function measured with virtual water maze test
Outcome Description:
The hippocampal function will by studies in a longitudinal manner and thus we plan to measure the water maze test performance at several time points (time frames) of the study.
Outcome Time Frame:
day 0
Safety Issue:
No
Principal Investigator
Alexander Storch, MD
Investigator Role:
Principal Investigator
Investigator Affiliation:
Dresden University of Technology
Authority:
Germany: Ethics Commission
Study ID:
EK153052009
NCT ID:
NCT01111396
Start Date:
February 2010
Completion Date:
Related Keywords:
- Acute Lymphatic Leukemia
- ALL
- GMALL 2003
- Chemotherapy
- Hippocampus
- Leukemia
- Leukemia, Lymphoid