Weight Loss to Reduce Breast Cancer Risk Factors
In sum, excess body weight and inactivity have emerged as strong avoidable causes of
postmenopausal breast cancer, with the greatest potential for primary prevention occurring
during the premenopausal years. However, surprisingly, no study to date has examined the
effects of a standard behavioral weight loss intervention on breast cancer risk markers in
premenopausal women. Understanding the effects of weight loss in premenopausal women is a
critical next step in existing research and will inform the development of future breast
cancer primary prevention programs. The purpose of this study is to determine the
feasibility of recruiting, treating, and retaining 20 overweight/obese women in a 12-week
randomized control trial examining feasibility and effects of a behavioral weight loss
program on breast cancer risk markers in premenopausal women. Participants will be randomly
assigned to either a 12-week comprehensive behavioral weight loss program (n=10) or control
condition (n=10). All women will be assessed at baseline and after 3 months of treatment.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention
Weight loss for one group
One group in this randomized study will be focused on weight loss during a 3 month period. The goal is to acheive a 6% weight loss during this time. Specific blood draws will be conducted pre and post weight loss to measure any hormonal changes due to this weight loss.
Suzanne Phelan, PhD.
California Polytechnic State University-San Luis Obispo
United States: Institutional Review Board
|California Polytechnic State University||San Luis Obispo, California 93407|