Efficacy of Thoracic Paravertebral Block in Reducing Chronic Pain and Disability After Breast Cancer Surgery With Axillary Lymph Node Dissection
Sixty percent of breast cancer patients undergo some form of breast surgery in the treatment
of the early stages of the disease. The recovery from surgery can be associated with severe
disabling pain persisting beyond 12 months after surgery. Research in pain has shown that
early intervention of acute pain can prevent long term chronic pain.
At The Ottawa Hospital, patients receive either paravertebral blocks or wound infiltration
with local anesthetic for postoperative pain management. We would like to compare these two
methods of pain control to determine an analgesic technique that will reduce acute and
chronic pain, and maximally improve long-term functional recovery and patient's quality of
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
The proportion of individuals reporting chronic postoperative pain 12 months following breast cancer surgery with lymph node dissection. Chronic pain will be defined by a Numeric Rating Scale (NRS) score of >3 (rest or with arm movement).
Michelle Chiu, MD
The Ottawa Hospital / Ottawa Health Research Institute
Canada: Ethics Review Committee