Know Cancer

or
forgot password

Molecular Correlates and Clinical Significance of Positron Emission Tomography With FET-PET in Combination With Perfusion-weighted Magnetic Resonance Imaging (PWI) in Patients With Low Grade Gliomas


N/A
18 Years
N/A
Open (Enrolling)
Both
Astrocytoma, Oligoastrocytoma, Oligodendroglioma

Thank you

Trial Information

Molecular Correlates and Clinical Significance of Positron Emission Tomography With FET-PET in Combination With Perfusion-weighted Magnetic Resonance Imaging (PWI) in Patients With Low Grade Gliomas


Inclusion Criteria:



- neuroradiologically suspected low grade glioma (Astrocytoma WHOI-II,
Oligodendroglioma WHO II, Oligoastrocytoma WHO II)

- histological verification will be obtained either by microsurgery or by stereotactic
biopsy

- patients older than 18 years

- Karnofsky Performance Score >=70

- pregnant or nursing female patients will not be included in this study

Exclusion Criteria:

- patients in whom informed consent cannot be obtained due to organic brain syndrome or
insufficient language skills

- patients who cannot lie quiet for a time period of app. two hours during the FET-PEt
scan

- medical history of a metastatic brain disease

- patients in whom an MRI scan cannot be performed due to claustrophobia metallic
protheses or pacemakers etc.

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

Overall survival

Outcome Time Frame:

24 months

Safety Issue:

No

Principal Investigator

Joerg C. Tonn, Prof. Dr.

Investigator Role:

Principal Investigator

Investigator Affiliation:

Department of Neurosurgery, LMU Munich

Authority:

Germany: Federal Office for Radiation Protection

Study ID:

GGN-CP4

NCT ID:

NCT01089244

Start Date:

June 2008

Completion Date:

April 2013

Related Keywords:

  • Astrocytoma
  • Oligoastrocytoma
  • Oligodendroglioma
  • Low grade glioma
  • Astrocytoma
  • Molecular imaging
  • FET PET
  • Therapy monitoring
  • Temodar
  • Astrocytoma
  • Glioma
  • Oligodendroglioma

Name

Location