Inclusion Criteria:

1. Has a history of surgically resected and pathologically proved AJCC stage I or stage
II adenocarcinoma of the head, neck, or uncinate of the pancreas.

2. Has been a participant in Hopkins IRB protocol (J0810) application number 00-01-58-58
entitled, "A randomized three-arm neoadjuvant and adjuvant feasibility and toxicity
study of a GM-CSF secreting allogeneic pancreatic cancer vaccine administered either
alone or in combination with either a single intravenous dose or daily metronomic
oral doses of cyclophosphamide for treatment of patients with surgically resected
adenocarcinoma of the pancreas"( the J0810 cohort), or have never received any type
of pancreatic cancer vaccine/immunotherapy, had the Whipple surgery within 18 months
and completed the planned adjuvant chemotherapy and /or chemoradiation (the vaccine
naive cohort).

3. Has provided informed consent.

4. Has received the last irradiated GM-CSF transfected allogeneic pancreatic cell
lines Panc 10/05/Panc 6.03 at least six months prior (+/- 1 month).Not applicable to
the vaccine-naive cohort patients.

5. Has received the last anti-cancer therapy at least 28 days ago.

6. Has an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.

7. Has adequate hematologic function.(Hemoglobin ≥ 9 g/dL ANC ≥ 1500/mm3 Platelets ≥
100,000 K/ mm3).

8. Has adequate renal function? (Serum creatinine ≤ 2 mg/dL).

9. Has adequate hepatic function. (Bilirubin ≤ 2.0 mg/dl, unless known Gilbert's
Syndrome; AST, ALT and amylase ≤ 2x upper limit of normal, Alk Phos ≤ 5x upper limit
of normal).

10. Agree to use adequate birth control, if of childbearing potential.

Exclusion Criteria:

1. Has radiographic evidence of pancreatic cancer recurrence.

2. Has any documented history of autoimmune diseases including systemic lupus
erythematosus, sarcoidosis, rheumatoid arthritis, glomerulonephritis,or vasculitis.

3. Has any uncontrolled medical problems.

4. Has had systemic steroid therapy within 28 days before vaccine administration.

5. Has an anticipated need for systemic steroid therapy within 28 days after vaccine
administration.

6. Has any evidence of active infections.

7. Is pregnant.

8. Has a history of another cancer (other than pancreatic cancer) in the past five years
except for treated non-melanoma skin cancer, superficial bladder cancer, or carcinoma
in-situ of the cervix.

9. Has a history of noncompliance during previous vaccination cycles with study
treatment and/or monitoring which is concerning for continued noncompliance.