Does Hounsfield Unit (HU) Predict the Detection of Cystic Renal Malignancy of Complicated Renal Cysts?
Even though there have been many trials and errors to enhance the diagnostic accuracy of CT
scans for complicated cysts, the trial to obtain the enhanced accuracy using CT scan would
be still valuable, when we consider its widespread use. A previous study demonstrated that
the enhancement of HU with intravenous administration of contrast material on CT scan by 15
HU would be "almost always indicative of a pathologic process although not always a
malignancy", another study showed the cut-off as 42 or 47 HU gap would be helpful in the
prediction of renal malignancy.
Observational Model: Case Control, Time Perspective: Retrospective
additional diagnostic criteria of CT to diagnose and predict the detection and recurrence of cystic RCC in the patients with complicated renal cysts
First, the primary outcomes is to determine cut-off values of maximal HU and the maximal gap of HU (HU of early excretory phase minus that of non-enhanced phase in CT scan)to predict the detection of renal malignancy. Some clinical factors (age, height, body weight, etc) were also included in the analysis. Second, the above-mentioned factors were included in the analysis of risk factors for recurrence of complicated renal cysts to determine the cut-off values.
Cheol Kwak, M.D.,Ph.D.
Seoul National University Hospital
Korea: Institutional Review Board