Randomized Controlled Trial Comparing Conventional and Fast Track Multi-Discipline Treatment Interventions for Colorectal Cancer
Laparoscopic Surgery, Fast Track Treatment and XELOX Chemotherapy have been introduced in
the treatment of colorectal cancer. All of these procedures are contributed to reduce the
hospitalization stay. However, the most economical mode for combination of these procedures
is still unclear. This is a randomized controlled study, a new notion"Fast Track
Multi-Discipline Treatment" is proposed, which is the combination of the Laparoscopic
Surgery, Fast track perioperative treatment during perioperative period and XELOX
Chemotherapy. The purpose of this study is to compare the Fast Track Multi-Discipline
Treatment with the conventional treatment(Open Surgery with conventional treatment during
perioperative period and mFolfox6 chemotherapy) for colorectal cancer on several aspects
like the average hospitalization day, complications, costs and quality of life.The focus of
the study will be to investigate whether the Fast Track Multi-Discipline Treatment reduces
hospital stay with similar complications compared with conventional perioperative treatment.
Moreover, the trial will clarify whether laparoscopic surgery is essential for Fast Track
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
The overall hospitalization stay during treatment from the first day in hospital to leave hospital when finish adjuvant chemotherapy or surgery (for patients who don't need chemotherapy).
6-month post surgery
Ke-Feng Ding, PhD/MD
The Second Affiliated Hospital, and The Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Zhejiang University College of Medicine.
China: Ministry of Health