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Genome Wide SNP Array-based Approach to Detect Micro-cytogenetic Lesions and KIT Mutation to Improve Treatment Outcomes in Patients With Core-binding Factor Positive Acute Myeloid Leukemia


N/A
18 Years
N/A
Open (Enrolling)
Both
Myeloid Leukemia

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Trial Information

Genome Wide SNP Array-based Approach to Detect Micro-cytogenetic Lesions and KIT Mutation to Improve Treatment Outcomes in Patients With Core-binding Factor Positive Acute Myeloid Leukemia


Inclusion Criteria:



- patients with core binding factor positive acute myeloid leukemia

- 18 years or older

- patients were treated with standard chemotherapy

- patients with available medical record and stored bone marrow specimen at time of
diagnosis

Exclusion Criteria:

- no definive criteria

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Retrospective

Outcome Measure:

response rate

Outcome Time Frame:

within 1 month after enrollment

Safety Issue:

No

Principal Investigator

Dong Hwan Kim, M.D.,Ph.D.

Investigator Role:

Principal Investigator

Investigator Affiliation:

Division of Hematology and Oncology/Samsung Medical Center

Authority:

South Korea: Institutional Review Board

Study ID:

2009-10-069

NCT ID:

NCT01066286

Start Date:

February 2010

Completion Date:

Related Keywords:

  • Myeloid Leukemia
  • genome wide SNP-array
  • micro-cytogenetic lesion
  • KIT mutation
  • core binding factor
  • acute myeloid leukemia
  • The Approval status was changed from Pending to Approved.
  • Leukemia
  • Leukemia, Myeloid, Acute
  • Leukemia, Myeloid

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