Inclusion Criteria:

- Histologically confirm epithelial carcinoma, verified to be positive for the
targeting antigen(Ep-CAM/epithelial glyco protein 2)according to the criteria given
below.

- Tumor specimens verified to be positive for the targeting antibody,i.e.EGP2 positive
(MOC31) by immunocytochemical or histochemical staining.

- Signed written informed consent

- Patients with no clinically symptomatic central nervous system (CNS) involvement.

- Both gender, age 18 -75 years old.

- Life expectancy of at least 3 months

- Eastern Cooperative Oncology Group (ECOG) Performance status 0-2

- Adequate hematologic, renal and hepatic function defined as: Neutrophils > 1.5 x
10^9/L;Platelets > 100 x 10^9/L; Creatinine < 120 umol/L; Total bilirubin within
normal range. Liver enzymes (ALAT and ASAT <2.5 UNL: alkaline phosphatase < 1.5 UNL
and yGT < 1.5 UNL).

- Coagulation parameters (pT, PTT) within normal range.

Exclusion Criteria:

- No medical history of Hepatitis B or C infection

- Patients must have no ECG abnormalities

- Patients must not be HIV positive

- Female premenopausal patients should not be pregnant (must have a negative pregnancy
test prior to inclusion) and should not be lactating.

- Patients must use effective contraception if of reproductive potential.

- Prior chemotherapy and/or radiation should be completed for at least 4 weeks prior to
study enrolment