A Pilot Study of Chemo-prevention of Green Tea in Women With Ductal Carcinoma in Situ (DCIS)
Many studies have shown that green tea may have anti-cancer and anti-inflammatory effects in
cancer cells and animal models of breast cancer. Some studies have found that Asian women
who drink many cups of green tea have lower rates of breast cancer. Green tea may have an
effect on proliferative and inflammatory pathways. Women with ductal carcinoma in situ
(DCIS) have been found to have inflammation in the breast tissue surrounding DCIS lesions.
Inflammatory pathways are being studied for a possible link to cancer. This study is
designed to evaluate changes in biomarkers of proliferation, inflammation, and angiogenesis
in response to green tea intake.
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention
Percent change in K167 staining
Prior to starting study and after 4-6 weeks of treatment
Nora Jaskowiak, MD
University of Chicago
United States: Food and Drug Administration
|The University of Chicago||Chicago, Illinois 60637|