A Study of Novel Magnetic Resonance Imaging Sequences for Target Delineation and Prognostication in Cervical Cancer
At our institution, all patients receiving external beam and/or brachytherapy as part of the
treatment of primary cervical cancer receive CT, PET, and MRI simulation scans as standard
of care. Brachytherapy patients also receive weekly T1/T2 weighted MR simulation scans as
part of their treatment planning.
We propose the use of additional MR sequences to the standard T1/T2 weighted MR simulation
scans. The data obtained from these additional sequences will be used for improving tumor
delineation and obtaining prognostic information.
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
The primary objective is to detect differences in MR spectroscopy, diffusion weighted MR, diffusion tensor imaging (DTI) or dynamic contrast enhancement (DCE) MR imaging between primary cervical tumors and normal cervical tissue.
Washington University School of Medicine
United States: Institutional Review Board
10-0033 / 201109278
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