Inclusion Criteria

Inclusion criteria;

1. Japanese male and female aged >or=20 to <80 years at obtaining informed consent

2. Patient with histologically or cytologically diagnosed solid tumor

3. Patient who is FRα-positive confirmed by immunohistochemistry (IHC) (except for
ovarian cancer that FRα-positive is frequently reported)

4. Patients with a folate-receptor alpha expressing solid tumor who are not responsive
or resistant to standard therapy and have no other appropriate treatment

5. Performance Status (PS) is 0 to 1 by Eastern Cooperative Oncology Group（ECOG）criteria

Exclusion criteria

1. Brain metastasis presenting clinical symptoms or requiring medical treatment

2. Serious and systemic infection requiring medical treatment

3. History of hypersensitivity to protein formulations including monoclonal antibody

4. With other active malignancy (except for carcinoma in situ)

5. With a large volume of pleural effusion or ascites requiring drainage