A Randomized Trial Evaluationg Resistance Training and Dietary Supplements as Intervention for Regaining Muscle Mass Following Radiotherapy in Head and Neck Cancer Patients
Head and neck cancer patients experience a significant loss of muscle mass following
radiotherapy treatment due to cachexia and dysphagia. This negatively affects muscle
strength and functional capacity.
Studies on healthy individuals and various groups of patients show that resistance training
in combination with protein and creatine ingestion is an effective means of increasing
muscle mass, strength and functional capacity.
Thus the aim is to investigate the following:
- is resistance training and dietary supplements tolerable among head and neck cancer
- the effect of the intervention on muscle mass, strength and functional capacity
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Supportive Care
Muscle mass and muscle strength
Jens Overgaard, Professor, MD
Denmark: The Danish National Committee on Biomedical Research Ethics