A Pilot Study to Compare the Nicotine Lozenge and Tobacco-Free Snuff for Smokeless Tobacco Reduction
In this study, we will enroll 80 subjects who will be randomized to either the nicotine
lozenge or tobacco-free snuff to reduce their ST use over 8 weeks with follow-up at 12
weeks. Forty subjects will be recruited at Mayo Clinic in Rochester, MN, and 40 subjects
will be recruited at the Oregon Research Institute in Eugene, Oregon.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
To compare the efficacy of nicotine lozenges and tobacco-free snuff for the reduction of ST use among ST users who have no intention of quitting tobacco.
Jon O Ebbert, MD
United States: Food and Drug Administration
|Mayo Clinic||Rochester, Minnesota 55905|
|Oregon Research Institute||Eugene, Oregon 97403|