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Short Term Effects of Photodynamic Therapy in Basal Cell Carcinoma

Phase 1
18 Years
Not Enrolling
Basal Cell Carcinoma

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Trial Information

Short Term Effects of Photodynamic Therapy in Basal Cell Carcinoma

Background and Aim: Basal cell carcinoma (BCC) is the most common skin cancer .Photodynamic
therapy _as a novel , non-invasive therapeutic approach _may be considered a valuable
strategy. This study was designed with the aim of the evaluation of efficacy of PDT in
treatment of BCC and factors that may affect response rate.

Materials and Methods: This was a clinical trial which was done on 28 BCCs. Patients were
treated with ALA-PDT monthly for 1-6 sessions and evaluated for clinical response,cosmetic
results and probable side effects.

Inclusion Criteria:

- Histologically proven BCCs

Exclusion Criteria:

- Rodent ulcer

- Morphea type

- ANA +

- History of photosensitivity or photodermatosis or ingestion of phototoxic

- Drugs during last month

- Pregnancy

- Breast feeding

- Age< 18

- History of another therapeutic intervention for bcc during last 6 months

Type of Study:


Study Design:

Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Principal Investigator

Zohreh Tehranchi-nia,

Investigator Role:

Principal Investigator

Investigator Affiliation:

Skin Research Center


Iran: Ethics Committee

Study ID:




Start Date:

January 2008

Completion Date:

September 2008

Related Keywords:

  • Basal Cell Carcinoma
  • basal cell carcinoma
  • photodynamic therapy
  • photo chemotherapy
  • basal cell epithelioma
  • Carcinoma
  • Carcinoma, Basal Cell