The Effects of Ankle Foot Orthoses on Gait Efficiency in Children With Acute Lymphoblastic Leukemia and Foot Drop
1. This study will determine the impact of Ankle Foot Orthoses (AFO) wear on gait
efficiency in children with ALL and Chemotherapy-Induced Peripheral Neuropathy (CIPN).
2. The study hypothesizes that children with CIPN will have lower net oxygen consumption
during the six minute walk test while wearing AFO as compared to their net oxygen
consumption during a six minute walk test while not wearing AFO.
3. The study will assess whether gait efficiency while using an AFO persists after one
month of use.
4. The study will hypothesize that the benefits of AFO use on gait efficiency persist
after one month of wear.
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Supportive Care
Primary outcome of this study will analyze the net oxygen consumption during the six minute walk test among study participants under the two walking conditions, with and without AFO.
Kirsten K Ness, PT, Ph.D
St. Jude Children's Research Hospital
United States: Institutional Review Board
|St. Jude Children's Research Hospital||Memphis, Tennessee 38105-2794|