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Rare And Cutaneous Non-Hodgkin Lymphoma Registry


N/A
N/A
21 Years
Open (Enrolling)
Both
Lymphoma, Lymphoproliferative Disorder

Thank you

Trial Information

Rare And Cutaneous Non-Hodgkin Lymphoma Registry


OBJECTIVES:

- To determine the clinical features, treatment, and outcome of patients with rare or
cutaneous pediatric non-Hodgkin lymphoma (NHL).

- To determine the pathologic and biologic features of these diseases, including
molecular diagnostics and flow cytometry.

- To establish a bank of these pathologically reviewed diseases and make specimens of
blood and tissue available to qualified researchers.

- To determine sub-groups of these diseases that could be targeted for future biologic,
pathologic, or therapeutic studies.

OUTLINE: On study data will include presenting symptoms and signs, physical description of
the tumor if it is on the skin, results of metastatic evaluation, stage (if available),
blood count, markers, and the results of viral serologies. Any existing underlying
conditions that could predispose to lymphoma will also be noted.

Demographic and outcomes data will be stored and maintained by the COG Research Data Center.
Demographic data will be linked to the specimen data in the BPC database.

The approach of this study is prospective data collection, including central pathologic
review, relevant biologic studies, submission of material to the Biopathology Center (BPC)
and collection of diagnostic and outcome data. Participants will be registered with a
standard COG registration form for documentation of age, gender, race, date of diagnosis,
initial presentation, initial work-up, and stage according to the standard staging for the
specific disease, initial diagnostic procedure, and institutional diagnosis. Tissue will be
sent according to guidelines in Section 4.0. Follow-up data, including relapse or
progression and vital status will be reported annually for 5 years.

Patients will be followed annually for 5 years and data will be collected including vital
status, evidence/absence of disease, type of treatment received, progression/relapse and
whether the patient continues on study.

Inclusion Criteria


DISEASE CHARACTERISTICS:

- Diagnosis of non-Hodgkin lymphoma (NHL)

- Any histology, except for Burkitt or Burkitt-like, diffuse large B-cell,
anaplastic large cell, or lymphoblastic lymphoma

- Primary CNS, primary cutaneous NHL, or lymphoproliferative diseases of any
histology allowed

- Pathological specimen from site not treated within the past 6 months

- Must have specimens available

PATIENT CHARACTERISTICS:

- Not specified

PRIOR CONCURRENT THERAPY:

- See Disease Characteristics

- At least 6 months since prior chemotherapy irradiation to study lesion

- At least 2 weeks since prior steroids

Type of Study:

Observational

Study Design:

N/A

Outcome Measure:

Clinical features, treatment, and outcomes

Safety Issue:

No

Principal Investigator

Amanda M. Termuhlen, MD

Investigator Role:

Study Chair

Investigator Affiliation:

Nationwide Children's Hospital

Authority:

Unspecified

Study ID:

CDR0000404164

NCT ID:

NCT01000753

Start Date:

May 2005

Completion Date:

Related Keywords:

  • Lymphoma
  • Lymphoproliferative Disorder
  • adult diffuse small cleaved cell lymphoma
  • adult diffuse mixed cell lymphoma
  • grade 1 follicular lymphoma
  • grade 2 follicular lymphoma
  • grade 3 follicular lymphoma
  • childhood immunoblastic large cell lymphoma
  • adult immunoblastic large cell lymphoma
  • mantle cell lymphoma
  • marginal zone lymphoma
  • small lymphocytic lymphoma
  • primary central nervous system non-Hodgkin lymphoma
  • cutaneous B-cell non-Hodgkin lymphoma
  • cutaneous T-cell non-Hodgkin lymphoma
  • lymphoproliferative disorder
  • Lymphoma
  • Lymphoma, Non-Hodgkin
  • Lymphoproliferative Disorders
  • Lymphoma, Large-Cell, Immunoblastic

Name

Location

National Naval Medical CenterBethesda, Maryland  20889
Roswell Park Cancer InstituteBuffalo, New York  14263
Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania  19104
Mayo Clinic Cancer CenterRochester, Minnesota  55905
Barbara Ann Karmanos Cancer InstituteDetroit, Michigan  48201
Hurley Medical CenterFlint, Michigan  48503
Medical City Dallas HospitalDallas, Texas  75230
University of Texas Health Science Center at San AntonioSan Antonio, Texas  78284-7811
Presbyterian - St. Luke's Medical CenterDenver, Colorado  80218
Van Elslander Cancer Center at St. John Hospital and Medical CenterGrosse Pointe Woods, Michigan  48236
Vanderbilt-Ingram Cancer CenterNashville, Tennessee  37232-6838
Marshfield Clinic - Marshfield CenterMarshfield, Wisconsin  54449
Newark Beth Israel Medical CenterNewark, New Jersey  07112
New York Medical CollegeValhalla, New York  10595
Holden Comprehensive Cancer Center at University of IowaIowa City, Iowa  52242-1002
Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsBaltimore, Maryland  21231-2410
Cleveland Clinic Taussig Cancer CenterCleveland, Ohio  44195
Brooke Army Medical CenterFort Sam Houston, Texas  78234-6200
Children's National Medical CenterWashington, District of Columbia  20010-2970
Children's Mercy HospitalKansas City, Missouri  64108
St. Joseph's Hospital and Medical CenterPaterson, New Jersey  07503
Children's Hospital and Regional Medical Center - SeattleSeattle, Washington  98105
Nemours Children's ClinicJacksonville, Florida  32207
All Children's HospitalSt. Petersburg, Florida  33701
Saint Jude Midwest AffiliatePeoria, Illinois  61637
Driscoll Children's HospitalCorpus Christi, Texas  78466
Cook Children's Medical Center - Fort WorthFort Worth, Texas  76104
Phoenix Children's HospitalPhoenix, Arizona  85016-7710
Southern California Permanente Medical GroupDowney, California  90242
Brooklyn Hospital CenterBrooklyn, New York  11201
Palmetto Health South Carolina Cancer CenterColumbia, South Carolina  29203
East Tennessee Children's HospitalKnoxville, Tennessee  37901
Children's Hospital of the King's DaughtersNorfolk, Virginia  23507
Midwest Children's Cancer Center at Children's Hospital of WisconsinMilwaukee, Wisconsin  53226
Arkansas Cancer Research Center at University of Arkansas for Medical SciencesLittle Rock, Arkansas  72205
Carol G. Simon Cancer Center at Morristown Memorial HospitalMorristown, New Jersey  07962
Jonathan Jaques Children's Cancer Center at Miller Children's HospitalLong Beach, California  90801
Kaiser Permanente Medical Center - OaklandSacramento, California  95825
Santa Barbara Cottage Children's HospitalSanta Barbara, California  93105
Lee Cancer Care of Lee Memorial Health SystemFort Myers, Florida  33901
Nemours Children's Clinic - OrlandoOrlando, Florida  32806
St. Joseph's Cancer Institute at St. Joseph's HospitalTampa, Florida  33607
St. Vincent Indianapolis HospitalIndianapolis, Indiana  46260
Blank Children's HospitalDes Moines, Iowa  50309
Ochsner Cancer Institute at Ochsner Clinic FoundationNew Orleans, Louisiana  70121
Alvin and Lois Lapidus Cancer Institute at Sinai HospitalBaltimore, Maryland  21215
Breslin Cancer Center at Ingham Regional Medical CenterLansing, Michigan  48910
Hackensack University Medical Center Cancer CenterHackensack, New Jersey  07601
Albert Einstein Cancer Center at Albert Einstein College of MedicineBronx, New York  10461
NYU Cancer Institute at New York University Medical CenterNew York, New York  10016
SUNY Upstate Medical University HospitalSyracuse, New York  13210
Mission Hospitals - Memorial CampusAsheville, North Carolina  28801
Rainbow Babies and Children's HospitalCleveland, Ohio  44106-5000
Baylor University Medical Center - HoustonHouston, Texas  77030-2399
Methodist Children's Hospital of South TexasSan Antonio, Texas  78229-3993
Primary Children's Medical CenterSalt Lake City, Utah  84113-1100
Providence Cancer Center at Sacred Heart Medical CenterSpokane, Washington  99220-2555
Edwards Comprehensive Cancer Center at Cabell Huntington HospitalHuntington, West Virginia  25701
Saint Peter's University HospitalNew Brunswick, New Jersey  08901-1780
UNMC Eppley Cancer Center at the University of Nebraska Medical CenterOmaha, Nebraska  68198-7680
Memorial Cancer Institute at Memorial Regional HospitalHollywood, Florida  33021
Childrens Hospital Los AngelesLos Angeles, California  90027
Lucile Packard Children's Hospital at Stanford University Medical CenterPalo Alto, California  95798
UCSF Helen Diller Family Comprehensive Cancer CenterSan Francisco, California  94115
Alfred I. duPont Hospital for ChildrenWilmington, Delaware  19803
Lombardi Comprehensive Cancer Center at Georgetown University Medical CenterWashington, District of Columbia  20007
AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston CampusAtlanta, Georgia  30322
Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical CenterSavannah, Georgia  31403-3089
University of Illinois Cancer CenterChicago, Illinois  60612-7243
Advocate Lutheran General Cancer Care CenterPark Ridge, Illinois  60068-1174
Lucille P. Markey Cancer Center at University of KentuckyLexington, Kentucky  40536-0093
CancerCare of Maine at Eastern Maine Medical CenterBangor, Maine  04401
Dana-Farber/Harvard Cancer Center at Dana-Farber Cancer InstituteBoston, Massachusetts  02115
University of Mississippi Cancer ClinicJackson, Mississippi  39216-4505
Siteman Cancer Center at Barnes-Jewish Hospital - Saint LouisSt. Louis, Missouri  63110
Children's HospitalOmaha, Nebraska  68114-4113
CCOP - Nevada Cancer Research FoundationLas Vegas, Nevada  89109-2306
St. Barnabas Medical Center Cancer CenterLivingston, New Jersey  07039
Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical SchoolNew Brunswick, New Jersey  08903
Herbert Irving Comprehensive Cancer Center at Columbia University Medical CenterNew York, New York  10032
Akron Children's HospitalAkron, Ohio  44308-1062
Nationwide Children's HospitalColumbus, Ohio  43205-2696
Dayton Children's - DaytonDayton, Ohio  45404-1815
Oklahoma University Cancer InstituteOklahoma City, Oklahoma  73104
Geisinger Cancer Institute at Geisinger HealthDanville, Pennsylvania  17822-0001
Penn State Children's HospitalHershey, Pennsylvania  17033-0850
Children's Hospital of Pittsburgh of UPMCPittsburgh, Pennsylvania  15213
Dell Children's Medical Center of Central TexasAustin, Texas  78723
West Virginia University Health Sciences Center - CharlestonCharleston, West Virginia  25302
Riley's Children Cancer Center at Riley Hospital for ChildrenIndianapolis, Indiana  46202-5225
Massachusetts General HospitalBoston, Massachusetts  02114-2617
University of Miami Sylvester Comprehensive Cancer Center - MiamiMiami, Florida  33136
Duke Cancer InstituteDurham, North Carolina  27710
Connecticut Children's Medical CenterHartford, Connecticut  06106
Children's Hospital Colorado Center for Cancer and Blood DisordersAurora, Colorado  80045
Nemours Children's Clinic - PensacolaPensacola, Florida  32504
Helen DeVos Children's Hospital at Spectrum HealthGrand Rapids, Michigan  49503
Legacy Emanuel Children's HospitalPortland, Oregon  97227
Children's Hospital of Alabama at University of Alabama at BirminghamBirmingham, Alabama  35233