A Single Blinded Randomized Controlled Trial of the Comparative Effects of Tamoxifen and Evening Primrose Oil in Premenopausal Non-high Risk Patients With Benign Breast Disease With Respect to the Estrogen Receptor Status.
Benign breast disease is frequently encountered in female patients, a significant proportion
of who are premenopausal women. Established methods of treatment do not yield significant
results. This is not only a social burden but also entails high economic cost. As such the
quality of life of these patients is a matter of concern for both the patients and their
families and to attending physicians. Reported effects of tamoxifen on benign breast disease
in premenopausal non high risk patients are scarce. Moreover published data has not yet
revealed association of estrogen receptors in different benign breast lesions.The
variability of response and its relation with estrogen receptor status is still a field of
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
Reduction of Lump Size.
Md. Tanveer Adil
Resident, Department of Surgery, Medical College and Hospital, Kolkata
India: Ministry of Health