Inclusion Criteria:

- Patients must fulfill all of the following criteria to be eligible for study entry:

- Those who will be eligible will be all patients with non-hematologic neoplasms
(lymphomas, leukemias, myeloma, myelodysplasia, or myeloproliferative syndromes) who
have disease which has been previously treated and/or for which there is no
acceptable standard treatment regimen available, and cannot be treated definitively
with either surgery or radiotherapy. All will be appropriate candidates for
treatment, and are not candidates for treatment with protocols of higher priority.
All patients should have an ECOG/Zubrod/SWOG performance status of <2 at the time of
the initiation of therapy, adequate end-organ function, no severe comorbid disease,
and ability to provide informed consent.

Other Eligibility Criteria:

- Signed Informed Consent

- ECOG/Zubrod/SWOG Performance Status <2 (Karnofsky Performance Status > 70%)

- Life expectancy > 8 weeks

- Male or female' age >18 years

- Patients of childbearing potential must be using an effective means of contraception.

- Women of childbearing potential must have a negative serum pregnancy test prior to
azacitidine treatment.

- Histologic diagnosis of a solid tumor malignancy that is advanced and cannot be
treated adequately by radiotherapy or surgery; or metastatic disease

- Baseline laboratory values (bone marrow, renal, hepatic):

- Adequate bone marrow function:

- Absolute neutrophil count >1000/µL

- Platelet count >100'000/µL

- Renal function:

- Serum creatinine < 1.5 x ULN

- Hepatic function:

- Bilirubin <1.5x normal

- Serum glutamic-oxaloacetic transaminase (SGOT) (aspartate aminotransferase
[AST]) or serum glutamic-pyruvic transaminase (SGPT) (alanine aminotransferase
[ALT]) levels <=2 x ULN

- Serum calcium < 12 mg/dl

Exclusion Criteria:

Patients meeting any of the following criteria are ineligible for study entry:

- Pregnant or lactating females

- Myocardial infarction or ischemia within the 6 months before Cycle 0' Day 0

- Uncontrolled' clinically significant dysrhythmia

- Prior radiotherapy to an indicator lesion unless there is objective evidence of tumor
growth in that lesion

- Uncontrolled metastatic disease of the central nervous system

- Sensitivity to erlotinib, 5-azacytidine or mannitol

- Advanced hepatic tumors

- Radiotherapy within the 2 weeks before Cycle 1' Day 1

- Surgery within the 2 weeks before Cycle 1' Day 1

- Any co morbid condition that' in the view of the attending physician' renders the
patient at high risk from treatment complications