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Acute and Longlasting Side Effects Caused by Radiotherapy in the Head and Neck Area


N/A
18 Years
N/A
Open (Enrolling)
Both
Mucositis of the Oral Mucosa, Dysphagia With Malnutrition, Xerostomia With Decreased Saliva Flow and Dental Defects

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Trial Information

Acute and Longlasting Side Effects Caused by Radiotherapy in the Head and Neck Area


The "Dental Team" at the Department for Oral and Maxillofacial Surgery in Trondheim takes
care of patients before, during and also after radiotherapy in the head and neck area. In
spite of the use of advanced radiation protocols and prevention measures such as
fluoridation splints the team observes significant side effects, both under radiation and
also on the long term after concluding treatment. Common problems are for example dermal and
mucosal damages, reduced salivation, dysphagia and lesions of the teeth. Aim of the study is
the investigation and documentation of side effects and complications in relation to the
oral cavity. During the acute and postradiation phase a continuous follow-up over a longer
lasting period is proceeded with registration of all relevant parameters. This includes
among others dental status and evaluation of quality of life.


Inclusion Criteria:



- radiation concerning the oral cavity

- follow-up at the Dental Team

Exclusion Criteria:

- refused approval

- survival prognosis under one year

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Principal Investigator

Christoph M Ziegler, Prof.Dr.Dr.

Investigator Role:

Study Director

Investigator Affiliation:

St.Olavs Hospital / NTNU

Authority:

Norway: Directorate of Health

Study ID:

17436

NCT ID:

NCT00995319

Start Date:

January 2008

Completion Date:

September 2012

Related Keywords:

  • Mucositis of the Oral Mucosa
  • Dysphagia With Malnutrition
  • Xerostomia With Decreased Saliva Flow and Dental Defects
  • Deglutition Disorders
  • Xerostomia
  • Malnutrition
  • Mucositis

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